The evidence for a specific effect of homoeopathic remedies is weak, according to a study. The investigators conclude that the clinical effects of homoeopathy are compatible with placebo effects. Aijing Shang and colleagues compared randomised placebo-controlled trials of homoeopathy with matched RCTs of allopathy. When the analysis was restricted to large trials of high quality there was no convincing evidence that homoeopathy was superior to placebo, whereas for conventional medicine an important effect remained